Premenstrual syndrome, addback therapy, leuprolide acetate, gnrh a, tibolone. Leuprolide lupron for prostate cancer chemoexperts. The injection site depends upon which formulation you are using, therefore the package insert should also be referenced to determine the appropriate injection site and method before. Eligard, lupron, lupron depot, lupron depotped, lupron depot3 month, lupron depot4 month, lupron3 month sr depot, prostap uk pharmacologic class. The kit consists of a twosyringe mixing system, a sterile safety needle table 3, a desiccant, and a package insert. It is a synthetic form of the naturally occurring gonadotropinreleasing. Leuprolide definition of leuprolide by medical dictionary.
Eligard is an injectable suspension of leuprolide acetate available in a single use kit. Most types of prostate cancer need the male hormone testosterone to grow and spread. Store in accordance with information listed on the product insert. For the role it plays in assisted reproductive technologies, leuprolide acetate is used to reduce the amount of estrogen and testosterone. Lupron depot leuprolide acetate for depot suspension fda. Lupron injection leuprolide acetate rx only description. Eligard, lupron, lupron depot leuprolide uses, side. Leuprolide fda prescribing information, side effects and. Leuprolide may cause shortterm within first 2 weeks of treatment increases in testosterone serum levels.
The nci drug dictionary contains technical definitions and synonyms for drugsagents used to treat patients with cancer or conditions related to cancer. Lupron, lupron depot leuprolide dosing, indications. Insulin syringes are used because the measurement on the syringe is in units i. When this is used for prostate cancer the resulting tumor flare can cause. This label reflects clinical trials for lupron depot in prostate cancer in which the majority of the subjects studied were at least 65 years of age. Leuprolide acetate lupron leuprolide acetate lupron is a gnrh agonist. Pdf dienogest is as effective as leuprolide acetate in treating the. Leuprolide definition of leuprolide by the free dictionary. It is used to treat a number of medical problems including. Initially, lupron, like other lhrh agonists, causes increases in serum levels of testosterone. These lupron depot formulations are not indicated for use in children. Leuprolide acetate injection is a sterile, aqueous solution intended for subcutaneous injection. Insert the plunger rod into the prefilled syringe containing sterile water, usp, and screw the plunger rod clockwise to tighten.
Leuprolide acetate definition of leuprolide acetate by. In other words, it tells the pituitary gland to ignore. Leuprolide injection is a synthetic manmade hormone that is similar to a natural hormone that is produced in the brain. It works by shrinking the abnormal uterine tissue that causes these. Leuprolide acetate leuprolide acetate dose, indications. Leuprorelin is the generic name of the drug and its inn and ban, while leuprorelin acetate is its banm and jan, leuprolide acetate is its usan and usp, leuprorelina is its dcit, and. Indication for lupron depotped leuprolide acetate for. Leuprolide overstimulates the bodys own production of certain hormones, which causes that production to shut down temporarily. Leuprolide acetate provider documents clinical inappropriateness to hormonal therapy and at least one of the following is occurring. Leuprolide acetate, an lhrh agonist, acts as a potent inhibitor of gonadotropin secretion when given continuously and in therapeutic doses. Indications for lupron depot leuprolide acetate for depot. If you have questions about this medicine talk to your.
Leuprolide works by decreasing the amount of testosterone in males and estrogen in females made by the body. A drug that is a synthetic polypeptide analog of naturally. Lupron, the patient should be apprised of the potential hazard to the fetus. Leuprolide acetate is administered as a subcutaneous injection using insulin syringes. Eligard is indicated for the palliative treatment of. Learn more about the word leuprolide, its origin, alternative forms, and usage from wiktionary. See other lupron depot and lupron injection package inserts for other. Preparation and evaluation of a phospholipidbased injectable gel. Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropinreleasing hormone receptor gnrhr agonist used for diverse clinical applications, including the treatment of. Leuprolide depot injection or implant medication guide note. Lupron depot leuprolide acetate for depot suspension 3. Leuprolide injection lupron depotped is used to treat central.
Norethindrone acetate as addback therapy with lupron 3. Menses usually returned within two months of cessation of therapy. See the lupron depot ped package insert for the use of leuprolide acetate in children with central precocious puberty. Leuprolide is used in men to treat the symptoms of prostate cancer but does not treat the cancer itself. Contraindications, warnings, and precautions in the norethindrone acetate package insert. Leuprolide reduces the amount of testosterone in men or. Definition of leuprolide acetate nci drug dictionary.
Leuprolide helps to reduce symptoms such as pelvic pain, painfulheavy menstrual periods, and abdominal bloating. Denosumab versus zoledronic acid for treatment of bone. Reconstitution after calculating the number of vials needed, using aseptic technique, reconstitute each vial of thymoglobulin with 5 ml of sterile water for injection, usp swfi. Leuprolide is used to treat advanced prostate cancer in men. Lupron depot leuprolide acetate for depot suspension. The kit consists of a twosyringe mixing system, a sterile needle table 2, a silicone desiccant pouch to control moisture uptake, and a package insert for constitution and administration procedures. Leuprolide is used in women to treat symptoms of endometriosis. Please see accompanying full prescribing information. Pdf dienogest is a selective progestin that has been investigated in a clinical trial programme for the treatment of. Measure prostatespecific antigen psa in first few weeks of therapy. The kit consists of a twosyringe mixing system, a sterile needle or a sterile safety needle table 2, a silica gel desiccant pouch to control moisture uptake, and a package insert. Follow the pictorial directions on the reverse side of this package insert for. Leuprolide injection eligard, lupron depot is used to treat the symptoms associated with advanced prostate cancer.